Definition of Darier disease (DAR/ Darier disease or Dyskeratosis Follicularis

Definition Darier disease (DAR/ Darier disease/ Dyskeratosis Follicularis / Darier–White disease/ Keratosis follicularis) is a rare, often chronic, genetic disorder characterized primarily by non-contagious skin changes. Darier disease or Keratosis Follicularis is an autosomal disorder, meaning that a single gene inherited from one parent causes this disease. Like Hailey-Hailey disease, Darier Disease is also grouped as a hereditary acantholytic dermatosis. Skin changes commonly start in adolescence. Flare-ups of Darier Disease or Keratosis Follicularis are triggered by tight-fitting clothes, humidity, stress and sun exposure. Darier disease affects both men and women equally and is not contagious. Majority of the patients develop symptoms of Darier Disease or Keratosis Follicularis before the age of 30. Many patients can also have this disease in a mild form of which they are not aware of. Individuals with severe Darier Disease have chronic relapsing-remitting symptoms. In some patie…



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